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The web-server iAMP-2L is a two-level multi-label predictor. It can be used to identify an uncharacterized peptide as antimicrobial peptide (AMP) or non-AMP according to its sequences information alone. If the uncharacterized peptide is identified as an AMP, the prediction will automatically be continued to identify it among the following five functional subfamilies: (1) antibacterial peptide, (2) anticancer/tumor peptide, (3) antifungal peptide, (4) Anti-HIV peptide, (5) Antiviral peptide. Note that an AMP may have more than one functional type.

The anticipated overall success rates for identifying AMPs or non-AMPs is over 86%, and that for identifying the functions of AMPs among the nine types is over 66%.